The US men's national team will not have five players to rely on for Tuesday's friendly in Mexico.

Christian Pulisic and Weston McKennie were among five players who left camp in October, US Soccer announced Sunday. Pulisic was released to his club AC Milan due to stress issues, while McKennie, full-back Marlon Fossey, goalkeeper Zack Steffen and striker Ricardo Pepi have left the club due to minor injuries

Pepi is being examined at his club PSV after taking a defensive shot to the face.

No more players will be added to the squad, leaving Mauricio Pochettino with 20 players to rely on for Tuesday's showdown in Guadalajara.

“As we have said before, we will always make decisions in the best interests of our players and respect the relationship we have with their clubs,” Pochettino said.

Pulisic assisted once and played 67 minutes in Saturday's 2-0 home game against Panama in Austin, Texas.

Pepi came off the bench before scoring the game-winning goal for the USMNT in second-half stoppage time. In total he played 23 minutes.

McKennie and Steffen were unused substitutes in Saturday's game, while Fossey didn't start.

The USMNT will be looking for their second-ever victory on Mexican soil this Tuesday, which would give Pochettino his second win as head coach.