The Indiana Pacers and Detroit Pistons begin their 2024-25 NBA season with a head-to-head matchup on Wednesday night in Detroit. The Pacers reached the Eastern Conference finals last season, but were defeated by the eventual world champion Boston Celtics. Meanwhile, the Pistons finished last in the East at 14-68 and tied the NBA record with a two-month, 28-game losing streak.

Tipoff from Little Caesars Arena in Detroit is scheduled for 7:00 p.m. ET. The SportsLine consensus lists Indiana as a 5-point favorite in the latest Pistons vs. Pacers odds, while the over/under for total points scored is 235 (see our NBA odds page for current odds for every game this week ). .

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