With hopes of a Premier League title fading further at the weekend, Arsenal must now refocus to navigate a difficult Champions League path when the Gunners visit Italian giants Inter on Wednesday.

The Gunners dropped points for the fifth time in 10 league games as they lost 1-0 to Newcastle. They were able to keep all 11 players on the pitch for 90 minutes but were unable to muster much attacking power. As a result, they fell back to fifth place in the table and are now a whopping seven points behind leaders Liverpool.

With seven points from their first three games they are reasonably well placed in the Champions League, but European away games have consistently thwarted Mikel Arteta over the years and this is as tough as it gets.

Having reached the Champions League final two years ago and winning the Scudetto last year, Inter are in a period of recovery at both domestic and European level. They are just one point behind the top of the Serie A table and are also in the important top eight in the Champions League table, having not conceded a single goal in the European Cup this season.

MORE: How to watch Inter Milan vs Arsenal in the Champions League

Inter Milan vs Arsenal Prediction, Odds

• Moneyline Lean: Inter (+160)
• Result prediction: Inter 2-0 Arsenal

To put it bluntly, Arsenal have been absolutely terrible away from home in European competition under Mikel Arteta.

Since the Spaniard took over in December 2019, Arsenal have won less than half of their European away games (9 out of 19), and eight of their nine wins have come in the Europa League. In last season's and this season's Champions League combined, they won just one (in Seville last October) of their six away games, losing three and drawing two.

Inter, on the other hand, have not conceded a goal in three Champions League games this season, including their heroic away performance at Man City. At home in European play, Inter have conceded just six goals in eleven home games since the start of the 2022/23 season, five of which came in a 2-0 loss to Bayern at the start of the 2022 group stage and a 3-3 draw with Benfica in the quarter-finals , with the overall victory largely secured. Remove these two games and it is a goal conceded in their last nine European home games.

Facts about the Inter Milan vs Arsenal game

• Date: Wednesday, November 6, 2024
• Kick-off time: 9:00 p.m. local time (3:00 p.m. ET / 12:00 p.m. PT)
• Location: San Siro (Milan, Italy)
• Referee: Istvan Kovacs (ROM)
• Last meeting: Inter – Arsenal 1:5 (November 25, 2003 | Champions League)

MORE: A complete guide to betting on soccer in the United States

Inter Milan vs Arsenal best bet

• Choose: Goalless first half (listed as “1st Half Result – Draw and Total Less than 1.5 Goals”)
• Opportunities: +160 (BetMGM)

Nobody in the Premier League took fewer shots in the first half than Arsenal. Nobody in Serie A took fewer shots in the first half than Inter.

Against Man City, Inter held their Premier League opponents under 1.0 xG in their goalless away draw in the first half and actually outscored City 10-9, with just four combined shots on goal from both teams and one combined big chance.

Neither team will be thrilled to open the attack in the first 45 minutes, with Arsenal likely happy to get out of the San Siro with a draw and Inter not wanting to risk falling behind unnecessarily. Unless there's a fluke goal or moment of brilliance (which, to be fair, is entirely possible), this game will go into halftime without an opener.

Inter Milan vs Arsenal Prop Bet

• Choose: Marcus Thuram to score or assist
• Opportunities: +160 (FanDuel)

• Choose: Marcus Thuram 2+ shots on goal
• Opportunities: +290 (FanDuel)

No one has scored more in the last month than Marcus Thuram. The France international hasn't really developed into a consistent threat in front of goal, but he remains a constant influence in the attacking third, regardless of whether he's putting the ball in the net.

After an explosive start to the season, things have dried up a bit for Thuram, but that can easily be attributed to simple random variance rather than a sign of a downturn. He came on as a substitute and scored the late winner in Young Boys' last Champions League game, and he has had two or more shots on goal in three of his last five Serie A games. He also scored five of his seven league goals and four of his five assists at San Siro.

While Lautaro Martinez is the club's biggest goal threat in league play, he often takes a back seat to other players in the Champions League, whether by design or because of his performance. Marco Arnautovic started the Young Boys game up front in place of Thuram, but that proved to be a big mistake as he was lazy out of play and missed a penalty. So you can assume that Thuram will return to the starting eleven here.