Alabama football is looking for a win over Missouri after the Crimson Tide's second loss of the season under new coach Kalen DeBoer.

No. 15 Alabama finds itself in a playoff-like scenario. It can't afford another loss if it wants to reach the top 12 of the College Football Playoff. The Crimson Tide has lost to No. 25 Vanderbilt and No. 7 Tennessee so far this season.

It now faces a No. 21 Missouri team that has lost just once this season: on the road to Texas A&M.

The matchup between the Crimson Tide and Tigers also marks the first homecoming game for DeBoer, who succeeded Nick Saban this season.

Kickoff is scheduled for 2:45 p.m. CT at Bryant-Denny Stadium. The game can be watched on ABC.

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Alabama Football Injuries Report

• Starting safety: Keon Sabb is out with a lower-body injury. He was expelled earlier this week. Reserve linebacker Cayden Jones is also out.
• Meanwhile, defensive back Red Morgan is listed as a game-time decision, according to Saturday afternoon's availability report released before kickoff.

Missouri injury report

• Starting quarterback Brady Cook is listed as a game-time decision on the injury report, which was released 90 minutes before kickoff.
• The Tigers start at running back. Nate Noel is out. Missouri is also without receiver Mookie Cooper, defensive end Darris Smith, quarterback Sam Horn, linebacker Khalil Jacobs and defensive end Joe Moore.