The potential for tirzepatide could ultimately propel Eli Lilly to a valuation of $1 trillion or higher in the future. The healthcare stock has plenty of room to rise as both Mounjaro and Zepbound are in early stages of growth. And while more competing weight-loss drugs are in development from other companies, it won't be easy to convince patients that there is a better option than tirzepatide, which has helped people in clinical trials lose nearly 27% of their body weight lose attempts.

Builders FirstSource is a big name in the construction industry as it is a major supplier of building products and materials and assists its customers with capital projects. A $10,000 investment in the company 10 years ago would be worth more than $390,000 today. Combined with the other $10,000 investments on this list, your total portfolio value would be about $1.17 million.

Strong demand for housing in recent years has helped boost developers' sales and profits. Over the last 12 months, the company reported a profit of $1.4 billion on revenue of just over $17 billion, resulting in a solid net margin of more than 8%. That's a dramatic increase from the $1.6 billion in total revenue and $18 million in profit the company generated in 2014.

As interest rates fall, capital projects and housing construction are likely to accelerate, which should lead to even greater growth for the company. Although demand hasn't been particularly strong this year, construction company stocks have rallied in recent months amid growing optimism that interest rates will be significantly lower in the near future. But no matter how quickly interest rates fall, Builders' position as a leader in construction and homebuilding can make it a solid long-term investment for your portfolio.

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David Jagielski has no position in any of the stocks mentioned. The Motley Fool has positions in and recommends Advanced Micro Devices and Nvidia. The Motley Fool has a disclosure policy.

Investing $10,000 in each of these three stocks 10 years ago would have netted you $1.1 million, was originally published by The Motley Fool